If you want to dance to electronic music Glam is the place. This popular dance club usually stays open until the wee hours of the morning, and hosts different parties such as Matilda which is a lesbian/women's night.
Tourist Be Aware
So, I was told before I arrived in Buenos Aires to be careful of my iPhone and the crime in this city. But the last thing I expected was to have my iPhone 6 and $1000AR stolen from my pocket while I was in the dark room having what i thought was fun but while i was getting busy with my pants down, I was getting robbed and it seems the security of the club are in on it I think. Anyway, be extremely careful what you get up to and who you take home from this club. If you own an iPhone, don't take it to this club. I understand from a friend that this happens all the time here. I have never had this happen to me ever and i travel around the world several times a year
Nice place, but I went on the wrong night
Glam is a smaller club. It's even a little difficult to find it in Palermo, but it's a lovely place. There are 2 dance floors. The main floor was basically playing cumbia and the other one was top40. The night I went (Friday) the crowd was 99% of lesbians. I guess there were 5 guys in there, including me. It was fun though.
Stay up and dance, dance, dance!
This is the gay club to hit if you want to stay out all night dancing. It doesn't even get going until 2 am or so. It very gay only two nights a week - Thursday and Saturdays (I think). It does charge a hefty (by Argie standards) cover charge, so be prepared to see lots of foreigners and locals looking to meet them. Drinks are also tourist priced - stick with the beer as the locals do. Not necessarily a locals bar anymore, but very fun nonetheless!